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Udinese vs. Inter 0-4 as it happened
Sassuolo and Torino were also supposed to battle it out for a Europa League placement but the game was postponed due to heavy fog.
Mancini could rely on the best defense of the league, while former Barcelona Martin Montoya made his debut in the starting XI.
Stevan Jovetic wrote his name on the score sheet for the first time since August 30, while Mauro Icardi scored a brace and Marcelo Brozovic netted his second goal this term.
Antonio Di Natale is reportedly thinking about a mid-season retirement and this could have been the last home game of his career.